Baskar Bakthavachalu, Senior Scientist at TIGS, was awarded the Wellcome Trust DBT India Intermediate Fellowship for his work on the role of Ribonucleoprotein granules in neuronal function and neurodegeneration using Drosophila as a model organism. RNA granules are dynamic, cytoplasmic assemblies that provide microdomains for intracellular mRNA regulation. Several RNA binding proteins contain intrinsically disordered regions (IDRs) capable of promoting irreversible protein assembly in vitro and in vivo. These protein aggregations are commonly observed in neurodegenerative conditions. Gain-of-function mutations in the IDRs have been shown to be associated with many forms of neurodegenerative disease, in particular, amyotrophic lateral sclerosis (ALS).
Farah Ishtiaq talks about her adventures as a field ecologist and using evolutionary ecology to understand how vector-borne diseases spread.
Dr Farah Ishtiaq is a Senior Scientist at TIGS, and she uses... read more
The discovery of antibiotics was a breakthrough in human history. After Alexander... read more
Ann Vinod, Communications Coordinator, Tata Institute for Genetics and Society, has around... read more
Wastewater epidemiology is an approach where the wastewater generated by humans is... read more
We congratulate Dr Anand T, member of the Stem Cell Research Group... read more
By Shweta Yadav Vertebrates, including humans, have a complex immune system, which constantly... read more
Dr. Baskar Bakthavachalu, Senior Scientist, Tata Institute for Genetics and Society, Bangalore,... read more
Harvinder Khera, Research Scientist at TIGS, won an Awsar Best Story Award,... read more
Ever since the Tata Institute for Genetics and Society (TIGS) began in... read more