Baskar Bakthavachalu, Senior Scientist at TIGS, was awarded the Wellcome Trust DBT India Intermediate Fellowship for his work on the role of Ribonucleoprotein granules in neuronal function and neurodegeneration using Drosophila as a model organism. RNA granules are dynamic, cytoplasmic assemblies that provide microdomains for intracellular mRNA regulation. Several RNA binding proteins contain intrinsically disordered regions (IDRs) capable of promoting irreversible protein assembly in vitro and in vivo. These protein aggregations are commonly observed in neurodegenerative conditions. Gain-of-function mutations in the IDRs have been shown to be associated with many forms of neurodegenerative disease, in particular, amyotrophic lateral sclerosis (ALS).
Farah Ishtiaq talks about her adventures as a field ecologist and using evolutionary ecology to understand how vector-borne diseases spread.
Dr Farah Ishtiaq is a Senior Scientist at TIGS, and she uses... read more
Baskar Bakthavachalu receives the SERB-STAR award
Dr. Baskar Bakthavachalu, Senior Scientist, Tata Institute for Genetics and Society, Bangalore,... read more
Factsheet on Malaria
Factsheet on Malaria read more
Sonia Sen talks about how her exposure to nature led her to study the brains of flies and mosquitoes
Sonia’s group at TIGS studies the development and the evolution of the... read more
Improving Sericulture with New Genetic Technologies
Though man discovered the use of silk cocoons in textiles some 5000... read more
Factsheet on AMR
Factsheet on AMR read more
The problem of insecticide resistance in mosquitoes
By Raja Babu Singh Kushwah Vector-borne diseases account for 7,00,000 deaths every... read more
The way to a vaccine
By Ashwathi V, Anirudha LakshminarasimhanSince December 2019, scientists all over the world... read more
Champions of TIGS
The novel Coronavirus (COVID-19) has affected almost every country in the world... read more
Test! Test! Test!
By Hemalatha Rao, Varun Chopra, Sonia Sen Illustrations by Hemalatha Rao As we sit... read more