Dr. Baskar Bakthavachalu, Senior Scientist, Tata Institute for Genetics and Society, Bangalore, has been awarded the prestigious SERB Science and Technology Award for Research (SERB-STAR), instituted to recognize and reward the outstanding performance of Principal Investigators of SERB projects. Baskar and his team studied the intrinsically disordered region (IDR) of the protein Ataxin-2 and its role in the formation of granules or amyloid filaments inside neurons. Their findings indicate that the IDR domain, though assists in the development of long-term memory, also causes specific forms of neurodegeneration. They deduce that this may be because the mechanisms that allow the formation and clearance of granules under normal conditions lean towards granule accumulation in diseased conditions. Baskar’s group is currently studying the cellular mechanism that regulates the Ataxin-2 granule assembly and also exploring therapeutic strategies to block/clear Ataxin-2 granules in iPSC and mouse ALS models.
Related Posts

Divij Kinger and team win MIT’s COVID19 challenge
Divij Kinger, Research Assistant at TIGS, won the ‘Space Conversion and Utility’ track with his team at MIT’s... read more
Pawan Kumar, a farmer from Karnataka, speaks about his challenges, on Kisan Diwas, 23 December 2020
Kisan Diwas or National Farmers’ Day is observed on December 23, the... read more

The way to a vaccine
By Ashwathi V, Anirudha LakshminarasimhanSince December 2019, scientists all over the world... read more

Improving Sericulture with New Genetic Technologies
Though man discovered the use of silk cocoons in textiles some 5000... read more

Baskar Bakthavachalu awarded The Wellcome Trust/DBT India Alliance Fellowship
Baskar Bakthavachalu, Senior Scientist at TIGS, was awarded the Wellcome Trust DBT... read more

Epigenetics and Health
By Dr Rakesh Mishra, Director, TIGS Organisms inherit their genetic make-up as a... read more

Venkata Sresty Tavva talks about new approaches in plant genetics research and their significance in improving food security
Dr. Venkata Sresty Tavva is the Group Leader of the Plant Genetics... read more

Sustainable Agriculture and Gene Editing Technologies
By Dr Deepak Pental, CSIR Distinguished Scientist and former Vice-Chancellor, University of... read more