Next-Generation Sequencing (NGS) denotes high-throughput sequencing in a massively parallel fashion that brought a huge impact at far lower cost using a variety of novel platform technologies. With its ultra-high throughput, scalability, and speed, NGS enables many applications that require sequences of DNA and/or RNA. The applications include whole-genome sequencing (WGS) of organisms that have multiple, large chromosomes requiring sophisticated algorithms for sequence assembly, analysis of temporal and spatial patterns of RNA expression, annotation of novel genomes and their encoded genes using bioinformatic tools, studies on the epigenetic changes in genomes, and analyses of single nucleotide polymorphisms and genetic signatures that either predict genetic disease susceptibility or the presence of desirable genetic traits. NGS also provides deep insights into the biological diversity and evolutionary history of populations, whether they are of viral, microbial, plant, or human origin.
Related Posts
PhD Admissions 2023
TIGS is proud to host a PhD program in collaboration with the... read more
Talk by Dr. Sresty Tavva at ‘Sugar rush with science’ event by C-CAMP
Dr. V S Sresty Tavva, Principal Scientist at TIGS recently delivered a... read more
The gene whispers
TIGS got featured in a newsroom article on the Tata group website.... read more
कोरोना के नए वैरिएंट
टाटा इंस्टीट्यूट फॉर जेनेटिक्स एंड सोसाइटी के निदेशक राकेश मिश्रा का कहना... read more
Dr. Farah’s Presentation at London
On May 16th Farah Ishtiaq, Principal Scientist, TIGS along with Dr. Angela... read more
The pursuit of a cure for hemophilia – Vasanth Thamodaran
History books, from as early as 2nd century AD, indicate knowledge of a... read more
Monkeypox is not COVID, but need to keep a watch, says top scientist
Monkeypox is not COVID kind of virus so there is no need... read more
Why environmental surveillance for avian influenza is vital
Wastewater-based epidemiology or pathogen surveillance has become an integral component of environmental surveillance... read more
TIGS scientists present their work at International conference on Genetics and Genomics in Health and Diseases
Scientists from TIGS presented their work at the recently concluded 8th Annual... read more