Dr. Baskar Bakthavachalu, Senior Scientist, Tata Institute for Genetics and Society, Bangalore, has been awarded the prestigious SERB Science and Technology Award for Research (SERB-STAR), instituted to recognize and reward the outstanding performance of Principal Investigators of SERB projects. Baskar and his team studied the intrinsically disordered region (IDR) of the protein Ataxin-2 and its role in the formation of granules or amyloid filaments inside neurons. Their findings indicate that the IDR domain, though assists in the development of long-term memory, also causes specific forms of neurodegeneration. They deduce that this may be because the mechanisms that allow the formation and clearance of granules under normal conditions lean towards granule accumulation in diseased conditions. Baskar’s group is currently studying the cellular mechanism that regulates the Ataxin-2 granule assembly and also exploring therapeutic strategies to block/clear Ataxin-2 granules in iPSC and mouse ALS models.
Related Posts

Anand T and team win MIT’s COVID19 Challenge
We congratulate Dr Anand T, member of the Stem Cell Research Group... read more

Biofilms: Beauties to See, Beasts to Treat
By Dr. Karishma S. Kaushik, MBBS, MD, PhD Savitribai Phule Pune University, Pune,... read more

A Unique Facility for Mosquito Research in the Country
Ever since the Tata Institute for Genetics and Society (TIGS) began in... read more

Pankaj Gupta receives The Wellcome Trust/DBT India Alliance IRMI travel grant for INORMS 2020
Pankaj Gupta, Program Manager at TIGS, received a travel grant to participate... read more

Divij Kinger and team win MIT’s COVID19 challenge
Divij Kinger, Research Assistant at TIGS, won the ‘Space Conversion and Utility’ track with his team at MIT’s... read more

Test! Test! Test!
By Hemalatha Rao, Varun Chopra, Sonia Sen Illustrations by Hemalatha Rao As we sit... read more

Sustainable Agriculture and Gene Editing Technologies
By Dr Deepak Pental, CSIR Distinguished Scientist and former Vice-Chancellor, University of... read more

The Making of CSIR-IGIB’s FELUDA
By Dr. Poorti Kathpalia, Science Communicator, with contributions from Dr. Debojyoti Chakraborty... read more