Surabhi Srivastava​

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Surabhi Srivastava
Chief Scientific Officer
Contact: surabhi [dot] srivastava [at] tigs [dot] res [dot] in

Education

  • Ph. D. (Molecular Biology), National Institute of Immunology, New Delhi
  • M. Sc. (Molecular & Human Genetics), Banaras Hindu University, Varanasi

Experience

  • Research Coordinator – Genomics and Bioinformatics, Centre for Cellular and Molecular Biology, Hyderabad (Oct 2018 – July 2022)
  • Project Scientist – Bioinformatics, Centre for Cellular and Molecular Biology, Hyderabad (Jan 2016 – Oct 2018)
  • Postdoctoral Fellow, Centre for Cellular and Molecular Biology, Hyderabad (Feb 2009 – Apr 2015)

Expertise

Expertise: Chromatin regulation, stem cell biology, Next Generation Sequencing (NGS)-based genomics and data analysis.​

Areas of interest

Epigenetics, genomics, data visualization (Blog: https://www.dataviz.in/)

Publications

  • SARS-CoV-2 seroprevalence in the city of Hyderabad, India in early 2021. Laxmaiah A et al., (2022) International Society for Infectious Diseases – IJID Regions Volume 2: 1-7
  • Host transcriptional response to SARS-CoV-2 infection in COVID-19 patients. Singh NK*, Srivastava S*, Zaveri L* et al. (2021) Clinical and Translational Medicine 11(9):e534
  • SARS-CoV-2 genomics: An Indian perspective on sequencing viral variants. Srivastava S, Banu S, Singh P, Sowpati DT, Mishra RK (2021) Journal of Biosciences 46: 22
  • Transcriptomic dataset of zebrafish tissues following chronic alcohol exposure and withdrawal. Banu S, Srivastava S, Mohammed A, Kushawah G, Sowpati DT, Mishra RK (2020) Data in Brief 33: 106442
  • Testing and surveillance strategies in the context of COVID-19 in India. Srivastava S*, Karak S*, Mishra RK (2020) Indian Chemical Engineer 62:4, 343-350
  • Tissue-specific transcriptome recovery on withdrawal from chronic alcohol exposure in zebrafish. Banu S, Srivastava S, Mohammed A, Kushawah G, Sowpati DT, Mishra RK (2020) Alcohol 91:29-38
  • Sperm methylome alterations following yoga‐based lifestyle intervention in patients of primary male infertility: A pilot study. Bisht S, Banu S, Srivastava S, Pathak RU, Kumar R, Dada R, Mishra RK (2020) Andrologia 00:e13551
  • Patterns of microsatellite distribution across eukaryotic genomes. Srivastava S, Avvaru AK, Sowpati DT, Mishra RK (2019) BMC Genomics 20(1):153
  • Epigenetic factors Polycomb (Pc) and Suppressor of zeste (Su(z)2) negatively regulate longevity in Drosophila. Dasari V, Srivastava S, Khan S, Mishra RK (2018) Biogerontology 19(1):33-45
  • C-State: An interactive web app for simultaneous multi-gene visualization and comparative epigenetic pattern search. Srivastava S*#, Sowpati DT*, Dhawan J, Mishra RK# (2017) BMC Bioinformatics 18 (Suppl 10):392
  • The placental gateway of maternal transgenerational epigenetic inheritance. Sailasree P, Srivastava S#, Mishra RK# (2017) Journal of Genetics 96(3):465-482
  • Epigenetic mechanisms and boundaries in the regulation of mammalian Hox clusters. Srivastava S#, Dhawan J, Mishra RK (2015) Mech Dev. 138 Pt 2:160-9
  • A ChIP-on-chip tiling array approach detects functional histone-free regions associated with boundaries at vertebrate HOX genes. Srivastava S, Sowpati DT, Garapati HS, Puri D, Dhawan J, Mishra RK (2014) Genomics Data 2:78-81
  • Vertebrate GAGA factor associated insulator elements demarcate homeotic genes in the HOX clusters. Srivastava S, Puri D, Garapati HS, Dhawan J, Mishra RK (2013) Epigenetics and Chromatin 6(1):8.| Highly Accessed
  • An ectopic CTCF dependent transcriptional insulator influences the choice of Vβ gene segments for VDJ recombination at TCRβ locus. Srivastava S*, Shrimali S*, Varma G, Grinberg A, Pfiefer K, Srivastava M (2012) Nucleic Acids Research 40(16):7753-65
  • Epigenetic profile of the euchromatic region of human Y chromosome. Singh NP, Madabushi S, Srivastava S, Senthil R, Neerja C, Khosla S, Mishra RK (2011) Nucleic Acids Research 39(9):3594-606
  • A functionally conserved boundary element from the mouse HoxD locus requires GAGA factor in Drosophila. Vasanthi D, Anant M, Srivastava S, Mishra RK (2010) Development 137(24):4239-47 18. Regulation of cellular chromatin state: insights from quiescence and differentiation. Srivastava S#, Mishra RK, Dhawan J (2010) Organogenesis 6(1):37-47

Book chapters

  • Epigenetic regulation of cis-regulatory elements and transcription factors during development. Khan S, Srivastava S# (2023) Translation Epigenetics, Perinatal and Developmental Epigenetics – Elsevier Book Volume 32: 71-113
  • Distinguishing States of Arrest: Genome-wide Descriptions of Cellular Quiescence Using ChIP-seq and RNA-seq Analysis. Srivastava S*, Gala H*, Mishra RK, and Dhawan J (2018) Methods in Molecular Biology, Cellular Quiescence – Springer Protocols 1686:215-239

Other articles

  • Building India’s Cell and Gene Therapy Ecosystem. Srivastava S, Thamodaran V. (Dec 2025) The India Forum
  • APSI: a pan-India consortium for monitoring pathogens via wastewater surveillance. Srivastava S., APSI consortium, et al. (Apr 2024) European Commission Joint Research Centre (JRC) | The International Conference “Towards a Global Wastewater Surveillance System for Public Health” – GLOWACON 2023 – The Conference Proceedings 94-96
  • Rare Genetic Diseases Research Summit Calls for Collaboration to Conquer Challenges. Meganathan S, Hegde S, Srivastava S. (Mar 2024) BioSpectrum India – Features
  • Unveiling the Power of Multi Stakeholder Engagement. Meganathan S, Srivastava S. (Feb 2024) BioSpectrum India – Features
  • Charting the Path: A Journey into Advancing Pathogen Surveillance Systems. Srivastava S. (Mar 2023) Alliance for Pathogen Surveillance Innovations (APSI)-India Outreach Articles
  • Alpha, Beta, Gamma, Delta – Where does it stop? Srivastava S. (Sep 2021) SciTales by CCMB
  • Epidemics, Pandemics May Become More Regular. Genome Sequencing Best Tool to Prepare. Srivastava S, Mishra RK. (June 2021) News18 Exclusive opinion
  • Learning From a Pandemic: Developing Capacity to Monitor COVID-19. Srivastava S, Karak S, Mishra RK. (Aug 2020) Science Reporter – NISCAIR
  • PDGFRα signaling in cardiac fibroblasts modulates quiescence, metabolism and self-renewal, and promotes anatomical and functional repair. Asli NS, et.al. (Jun 2019) bioRxiv 225979; doi: https://doi.org/10.1101/225979
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