K Thangaraj

K_Thangaraj

K Thangaraj
CCMB-TIGS Outstanding Scientist
thangaraj.k@tigs.res.in

Education

  • Ph.D. Genetics, University of Madras, Chennai, 1996
  • M.Phil. Genetics, University of Madras, Chennai, 1990
  • M.Sc. Zoology, University of Madras, Chennai, 1988

Experience

  • Director, Centre for DNA Fingerprinting and Diagnostics (CDFD), Hyderabad, 2020 – 2023
  • Director – Additional Charge, Institute for Stem Cell Science and Regenerative Medicine (inStem), Bangalore, Feb. 2022 – Aug. 2022
  • Chief Scientist, CSIR-Centre for Cellular and Molecular Biology, Hyderabad, 2014 – 2023
  • Scientist, CSIR-Centre for Cellular and Molecular Biology, Hyderabad, 1993 – 2014

Expertise

  • Population genomics and evolutionary biology
  • Molecular basis of
    – mitochondrial disorders
    – cardiovascular diseases
    – rare and recessive disorders
    – male infertility
    – sex determination
  • Ancient DNA and forensic genetics
  • Genetic susceptibility/resistance to infectious diseases
  • Genomics of Ayurveda, an Indian traditional medicine

Honors and Awards:

  • Legend of Hyderabad by Dr. Mohan Diabetes Speciality Centre, 26 May 2024.
  • Distinguished Lecture Award by Indian Society of Animal Genetics and Breeding, 23 August 2023.
  • Sir. Dr. U. N. Brahmachari Award by National Institute of Pharmaceutical Education and Research (NIPER), Kolkata, 19 July 2022.
  • Sun Pharma Research Award by Sun Pharma Science Foundation, 30th January 2019.
  • Distinguished Scientist Award by Andhra Pradesh Akademi of Sciences, 9th November 2018.
  • Excellence in Research Award by SciGenom Research Foundation 2 October 2017.
  • UKIERI (UK India Education and Research Initiative) Major Award, Presented by Gordon Brown, 2007.

Elected Fellowships

  • J C Bose Fellowship, SERB, Dept. of Science and Technology, Govt. of India
  • Indian National Science Academy, New Delhi
  • Indian Academy of Sciences, Bangalore
  • National Academy Sciences (India), Allahabad
  • National Academy of Biological Sciences, Chennai
  • Andhra Pradesh Akademi of Sciences, Hyderabad
  • Telangana Akademi of Sciences, Hyderabad

Member of Editorial Board

  • Associate Editor, BMC Medical Genomics
  • Associate Editor, Tropical Medicine and International Health
  • Member, Editorial Board, Human Genetics
  • Member, Editorial Board, Clinical Genetics
  • Member, Editorial Board, Mitochondrion

Selected Publications

  • Thangaraj K, Gupta NJ, Chakravarty B, Singh L (1998) A 47,XXY female. Lancet 352: 1121.
  • Thangaraj K, Chaubey G, Kivisild T, Reddy AG, Singh VK, Rasalkar AA, Singh L (2005) Reconstructing the origin of the Andaman Islanders. Science 308: 996. (accompanied with Perspectives by Peter Foster and Shuichi Matsumura)
  • Reich D*, Thangaraj K*, Patterson N*, Price AL*, Singh L (2009) Reconstructing Indian Population History. Nature. 461: 489-494. (*equal first authors)(with cover page and accompanied with News & Views by Aravinda Chakravarty)
  • Dhandapany PS, Sadayappan S, Xue Y, Powell GT, Rani DS, Nallari P, Rai TS, Khullar M, Soares P, Bahl A, Tharkan JM, Vaideeswar P, Rathinavel A, Narasimhan C, Ayapati DR, Ayub Q, Mehdi SQ, Oppenheimer S, Richards M, Price A, Patterson N, Reich D, Singh L, Tyler-Smith C, Thangaraj K (2009) A common MYBPC3 (Cardiac Myosin Binding Protein C) variant associated with cardiomyopathies in South Asia. Nat. Genet. 41 187 – 191.
  • Dhandapany PS, Razzaque Md A, Muthusami U, Kunnoth S, Edwards JJ, Mulero-Navarro S, Riess I, Pardo S, Sheng J, Rani DS, Rani B, Govindaraj P, Flex E, Yokota T, Furutani M, Nishizawa T, Nakanishi T, Robbins J, Limongelli G, Hajjar RJ, Lebeche D, Bahl A, Khullar M, Rathinavel A, Sadler KC, Tartaglia M, Matsuoka R*, Thangaraj K*, Gelb BD* (2014) RAF1 mutations cause dilated cardiomyopathy. Nat. Genet. 36: 635-639. (*equally directed the work)
  • Nakatsuka N, Moorjani P, Rai N, Sarkar B, Tandon A, Patterson N, Bhavani GS, Girisha KM, Mustak MS, Srinivasan S, Kaushik A, Vahab SA, Jagadeesh SM, Satyamoorthy K, Singh L, Reich D, Thangaraj K (2017) The promise of discovering population-specific disease-associated genes in South Asia. Nat Genet. 49: 1403-1407. (with cover page and accompanied by Editorial)
  • Harney É, Nayak A, Patterson N, Joglekar P, Mushrif-Tripathy V, Mallick S, Rohland N, Sedig J, Adamski N, Bernardos R, Broomandkhoshbacht N, Culleton BJ, Ferry M, Harper TK, Michel M, Oppenheimer J, Stewardson K, Zhang Z, Harashawaradhana, Bartwal MS, Kumar S, Diyundi SC, Roberts P, Boivin N, Kennett DJ*, Thangaraj K*, Reich D*, Rai N* (2019) Ancient DNA from the skeletons of Roopkund Lake reveals Mediterranean migrants in India. Nat Commun. 10:3670. (*contributed equally to this work)
  • Shinde V, Narasimhan VM, Rohland N, Mallick S, Mah M, Lipson M, Nakatsuka N, Adamski N, Broomandkhoshbacht N, Ferry M, Lawson AM, Michel M, Oppenheimer J, Stewardson K, Jadhav N, Kim YJ, Chatterjee M, Munshi A, Panyam A, Waghmare P, Yadav Y, Patel H, Kaushik A, Thangaraj K, Meyer M, Patterson N, Rai N, Reich D (2019) An Ancient Harappan Genome Lacks Ancestry from Steppe Pastoralists or Iranian Farmers. Cell. 179:729-735.