Alok Bhattacharya

alok

Alok Bhattachaarya
Honorary Visiting Professor
Contact: alok [dot] bhattacharya [at] tigs [dot] res [dot] in

Education

PhD, Jawaharlal Nehru University, New Delhi

Experience

  • Professor of Biology, Ashoka University, Sonipat
  • Professor & Dean of Life Sciences, Jawaharlal Nehru University, New Delhi
  • Dean School of Information Technology (currently School of Integrative and Computational Sciences), Jawaharlal Nehru University, New Delhi
  • Vice President, Indian National Science Academy , New Delhi

Expertise

  • Cell and Molecular biology
  • Bioinformatics and computational biology
  • Genomics and rare genetic disorders

Areas of interest

  • Biology and drug discovery of rare genetic disorders
  • Policy on rare genetic disorders
  • Clinical trial rules and simplification of procedures

Honors and awards

  • Robert McNamara Fellow of the World Bank ( 1985-1986 )
  • Rockefeller Biotechnology Career Development Award ( 1988-1990 )
  • Member Guha Research Conference (1992)
  • S.S. Bhatnagar award (1994)
  • Fellow, Indian National Science Academy, New Delhi (2000)
  • J.C. Bose Fellowship of DST (2008)
  • Aryabhata medal of INSA (2015)
  • Fellow, Indian Academy of Sciences, Bangalore (2014)
  • 12th Amar Nath Bhaduri Memorial Lecture on March 30th, 2017, Kolkata University
  • GJS Rao Memorial Lecture, Dept of Biochemistry, Indian Institute of Science, Bengaluru, Sept 20, 2016
  • Dr. J. Das Memorial lecture award by Indian Society of Cell Biology 2017
  • JV Bhat memorial Lecture, Manipal University, 2020

Relevant publications

  • Pinotsis N, Zielinska K, Babuta M, Arolas JL, Kostan J, Khan MB, Schreiner C, Salmazo A, Ciccarelli L, Puchinger M, Gkougkoulia EA, Ribeiro EA Jr, Marlovits TC, Bhattacharya A, Djinovic-Carugo K. Calcium modulates the domain flexibility and function of an α-actinin similar to the ancestral α-actinin. Proc Natl Acad Sci U S A. 2020 Sep 8;117(36):22101-22112. doi: 10.1073/pnas.1917269117. Epub 2020 Aug 26. PMID: 32848067; PMCID: PMC7486759.
  • Awasthi K, Srivastava A, Bhattacharya S., Bhattacharya A. 2020. Tissue-specific expression of the sialic acid metabolic pathway: Role in GNE myopathy. J Muscle Res Cell Motil. 2020 Oct 7. doi: 10.1007/s10974-020-09590-7.
  • Roychowdhury T, Singh VK, Bhattacharya A. (2018) Classification of pathogenic microbes using a minimal set of single nucleotide polymorphisms derived from whole genome sequences. Genomics. Feb 10. pii: S0888-7543(18)30092-2. doi:10.1016/j.ygeno.2018.02.004.
  • Bhattacharya S, Khadilkar SV, Nalini A, Ganapathy A, Mannan AU, Majumder PP, Bhattacharya A. (2018) Mutation Spectrum of GNE Myopathy in the Indian Sub-Continent. J Neuromuscul Dis. 5(1):85-92. doi: 10.3233/JND-170270. PubMed PMID: 29480215.
  • Mansuri MS, Bhattacharya S, Bhattacharya A. A novel alpha kinase EhAK1 phosphorylates actin and regulates phagocytosis in Entamoeba histolytica. PLoS Pathog. 2014 Oct 9;10(10):e1004411. doi: 10.1371/journal.ppat.1004411. eCollection 2014 Oct. PubMed PMID: 25299184; PubMed Central PMCID: PMC4192601
  • Katherine S. Ralston, Michael D. Solga, Nicole M. Mackey-Lawrence1, Somlata, Alok Bhattacharya & William A. Petri Jr (2014) trogocytosis by Entamoeba histolytica contributes to cell killing and tissue invasion. Nature, doi:10.1038/nature13242, 508, 526-530.
  • Ahmad HM, Muiwo P, Ramachandran SS, Pandey P, Gupta YK, Kumar L, Kulshreshtha R, Bhattacharya A. (2014) miR-22 regulates expression of oncogenic neuro-epithelial transforming gene 1, NET1. FEBS J. Sep;281(17):3904-19. doi:10.1111/febs.12926.
  • Somlata, Sathisha K., Mridula Agrahari, Mrigya Babuta Sudha Bhattacharya and Alok Bhattacharya (2012) Autophosphorylation of Ser428 of EhC2PK plays a critical role in regulating erythrophagocytosis in the parasite Entamoeba histolytica J. Biol. Chem. Vol. 287, Issue 14, 10844-10852, March 30, 2012
  • Somlata, Bhattacharya, S., Bhattacharya, A. (2011) A C2 domain protein kinase initiates phagocytosis in the protozoan parasite Entamoeba histolytica. Nat. Commun. 2, 230, doi: 10.1038/ncomms1199
  • Vaz, C., Ahmad, H. M., Sharma, P., Gupta, R., Kumar, L., Kulshreshtha, R. and Bhattacharya, A. (2010). “Analysis of microRNA transcriptome by deep sequencing of small RNA libraries of peripheral blood.” BMC Genomics 11(1): 288.
  • Nandi A., Vaz C., Bhattacharya A., Ramaswamy R. (2009) miRNA-regulated dynamics in circadian models. BMC Syst. Biol. May 5:3, 45.
  • Das S., Vishnoi A., Bhattacharya A. (2009) ABWGAT: Anchor based whole genome analysis tool. Bioinformatics Dec 15;25(24):3319-20. Epub 2009 Oct 14.
  • Vishnoi, A., Roy, R. & Bhattacharya, A. (2007) Comparative analysis of bacterial genomes: identification of divergent regions in mycobacterial strains using an anchor-based approach. Nucleic Acids Res. 35, 3654-3667.
  • Sahoo, N., Labruyere, E., Bhattacharya, S., Sen, P., Guillen, . & Bhattacharya, A. (2004) Calcium binding protein 1 of Entamoeba histolytica interacts with actin and is involved in dynamics of cytoskeleton. J. Cell Sci. 117, 3625-3634.