Shivranjani C Moharir

Shivranjani(crpfi)

Shivranjani C Moharir
Senior Scientist
shivranjani.c@tigs.res.in

Education

  • PhD, Centre for Cellular and Molecular Biology (CCMB), 2020
  • MSc, RTM Nagpur University, 2011

Experience

  • BCIL- Industrial Training, Mahabeej, Nagpur, 2011-2012
  • Post-doctoral research, SARS-CoV-2 surveillance in wastewater and air, CCMB, 2020-2021

Expertise

  • Cell and molecular biology, neurodegenerative diseases, pathogen surveillance

Areas of interest

Pathogen surveillance using wastewater-based epidemiology, development of diagnostic kits for rare genetic disorders, development of rice varieties with low glycemic index and enhanced level of protein, iron, and zinc

Publications

  • Identification of a splice variant of optineurin which is defective in autophagy and phosphorylation, Moharir SC, Bansal M, Ramachandran G, Ramaswamy R, Rawat S, Raychaudhuri S, Swarup G, BBA Molecular Cell Research, Volume 1865, Issue 11, Part A, November 2018, Pages 1526-1538, DOI: 10.1016/j.bbamcr.2018.08.009
  • Optineurin modulates ER stress-induced signaling pathways and cell death, Ramachandran G, Moharir SC, Raghunand TR, Swarup G, Biochemical and Biophysical Research Communications, Volume 534, 1 January 2021, Pages 297-302, DOI: 10.1016/j.bbrc.2020.11.091
  • Optineurin promotes autophagosome formation by recruiting the autophagy-related Atg12-5-16L1 complex to phagophores containing the Wipi2 protein, Bansal M, Moharir SC, Sailasree SP, Sirohi K, Sudhakar C, Sarathi DP, Lakshmi BJ, Buono M, Kumar S, Swarup G, 2018, Journal of Biological Chemistry, 293, 132-147, DOI: 10.1074/jbc.M117.801944
  • Autophagy receptor optineurin promotes autophagosome formation by potentiating LC3-II production and phagophore maturation, Bansal M, Moharir SC, Swarup G, 2018, Communicative and Integrative Biology, 2018 May 17;11(2):1-4, DOI: 10.1080/19420889.2018.1467189