Efficient allelic drive in Drosophila

Nature Communications | April 09, 2019

Gene-drive systems developed in several organisms result in super-Mendelian inheritance of transgenic insertions. Here, we generalize this “active genetic” approach to preferentially transmit allelic variants (allelic-drive) resulting from only a single or a few nucleotide alterations.[…]

Neurotransmitter identity: A question of lineage

elifesciences | May 7, 2019

The nervous system develops from a small number of neural stems cells that generate all the different types of neurons found in an organism. First, a process of spatial patterning imparts unique molecular identities to individual neural stem cells, making them distinct from one another […]

Heinrich Reichert

The Company of Biologists Ltd

Heinrich Reichert, Professor Emeritus at the University of Basel,
Switzerland, passed away on the 13th of June 2019 after a prolonged
illness. Heinrich described himself as ‘a hedonist when it came to
science’ because he said it gave him great pleasure. It was this quality
that made working with Heinrich thrilling and deeply fulfilling.[…]

A Near-Chromosome Level Genome Assembly of Anopheles stephensi

Frontiers in Genetics | November 16, 2020

Malaria remains a major healthcare risk to growing economies like India, and a chromosome-level reference genome of Anopheles stephensi is critical for successful vector management and understanding of vector evolution using comparative genomics. We report chromosome-level assemblies of an Indian strain, STE2, and a Pakistani strain SDA-500 by combining draft genomes of the two strains using a homology-based iterative approach.