Cell-Based Therapeutics

Stem cell based therapeutic platform employs both Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) – CRISPR-associated proteins (Cas) based gene editing approach and patient derived induced Pluripotent Stem Cells (iPSCs) to generate disease models for rare genetic disorders that are prevalent in India. We also use human Pluripotent Stem Cells (hPSCs) as a model system to study the role of RNA modifications in stem cell maintenance and differentiation.

Platform Coordinator: Vasanth Thamodaran

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